“What would robots do if humans took over?”* The joky question posed by Shagun Tripathi at the Global Peter Drucker Forum 2017 raises a fundamental issue. It prompts us to remember that the economy, technology, business and government are not givens – they are shaped by human choice. Yet it also forces us to recognize that the human perspective has been increasingly sidelined in the way we think about and enact the relations between technology and society, leaving the most precious, human, potential undervalued and underused. “Taking over” means actively shaping the organizations of the future and taking on a different mind-set: Should leaders in the 21st century become as good in understanding the human dimension as they are in grasping the latest scientific discovery, technology or management technique? Should they be able to frame challenges differently and ask different questions? At best, should we more actively manage the creation of our own future?